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Matt Donnelly

Matt Donnelly

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mjdonnelly@gibsondunn.com

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Expanded QSBS Benefits: What Biotech Founders Need to Know After the “One Big Beautiful Bill” Act

July 30, 2025 | Posted by Eric B. Sloan; Matt Donnelly; Kamia Williams; Bree Gong; Topic(s): Government Regulation; Tax; Trends and Insights

Why this matters for biotech start-ups

Raising capital for drug discovery often pushes early-stage biotech companies above the gross asset limit for qualifying for the U.S. federal income tax benefits associated with qualified small business stock (“QSBS”). The law commonly referred to as the One Big Beautiful Bill Act (the “OBBBA”), signed into law on July 4, 2025, lets founders and other investors greater access these tax savings—potentially reducing their tax bill by millions when the company is sold.

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