Welcome to Part 2 of our 2026 Life Sciences Industry Outlook series. Today, we are focusing on life sciences capital markets activity in 2025 and expectations for 2026.
The life sciences equity capital markets in 2025 were defined by a stark “tale of two halves,” beginning with intense volatility that effectively shuttered deal activity. The first half of the year was marred by significant market uncertainty, particularly following the “Liberation Day” tariff announcements. This event, combined with regulatory upheaval caused major indices like the XBI and Nasdaq to slide. During this period, the capital markets lay dormant—April saw zero priced biotech IPOs and only four priced follow-on deals, three of which were registered directs.